Publicaciones
Review: Leptin gene expression in the placenta--regulation of a key hormone in trophoblast proliferation and survival.
Maymó JL, Pérez AP, Gambino Y, Calvo JC, Sánchez-Margalet V, Varone CL.
Placenta. 2011 Mar;32 Suppl 2:S146-53. PubMed.
Leptin receptor activation increases Sam68 tyrosine phosphorylation and expression in human trophoblastic cells.
Sánchez-Jiménez F, Pérez-Pérez A, González-Yanes C, Najib S, Varone CL, Sánchez-Margalet V.
Mol Cell Endocrinol. 2011 Jan 30;332(1-2):221-7. PubMed.
Regulation of placental leptin expression by cyclic adenosine 5'-monophosphate involves cross talk between protein kinase A and mitogen-activated protein kinase signaling pathways.
Maymó JL, Pérez Pérez A, Dueñas JL, Calvo JC, Sánchez-Margalet V, Varone CL.
Endocrinology. 2010 Aug;151(8):3738-51. PubMed.
MAPK and PI3K activities are required for leptin stimulation of protein synthesis in human trophoblastic cells.
Pérez-Pérez A, Gambino Y, Maymó J, Goberna R, Fabiani F, Varone C, Sánchez-Margalet V.
Biochem Biophys Res Commun. 2010 Jun 11;396(4):956-60. PubMed.
17Beta-estradiol enhances leptin expression in human placental cells through genomic and nongenomic actions.
Gambino YP, Maymó JL, Pérez-Pérez A, Dueñas JL, Sánchez-Margalet V, Calvo JC, Varone CL.
Biol Reprod. 2010 Jul;83(1):42-51. PubMed.
Leptin stimulates protein synthesis-activating translation machinery in human trophoblastic cells.
Pérez-Pérez A, Maymó J, Gambino Y, Dueñas JL, Goberna R, Varone C, Sánchez-Margalet V.
Biol Reprod. 2009 Nov;81(5):826-32. PubMed.
Up-regulation of placental leptin by human chorionic gonadotropin.
Maymó JL, Pérez Pérez A, Sánchez-Margalet V, Dueñas JL, Calvo JC, Varone CL.
Endocrinology. 2009 Jan;150(1):304-13. PubMed
Leptin prevents apoptosis of trophoblastic cells by activation of MAPK pathway.
Pérez-Pérez A, Maymó J, Dueñas JL, Goberna R, Calvo JC, Varone C, Sánchez-Margalet V.
Arch Biochem Biophys. 2008 Sep 15;477(2):390-5. PubMed.
Leptin promotes cell proliferation and survival of trophoblastic cells.
Magariños MP, Sánchez-Margalet V, Kotler M, Calvo JC, Varone CL.
Biol Reprod. 2007 Feb;76(2):203-10. PubMed
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